The medicines from plant orgin, animal orgin and mineral orgin are collected, identified properly and cleaned. The ingredients for making powders are to be dried and pulverized separately and then homogenously mixed together and ground into the base as per the formula up to the proper consistency for making gulika. The medicines which require purification, are identified and purified as per the textual references and the purity analytically checked to ensure the medicine is devoid of side effects.

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