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Guluchyadi kashayam- Benefits, Ingredients, Indications, Dosage, Usage, Diet, Exercises, Side Effects


Guluchyadi kashayam is an Ayurvedic medicine for a wide array of diseases from rheumatoid arthritis to gastric ulcers. It cures many kinds of inflammations in the body.

Benefits of Guluchyadi kashayam

It is beneficial in conditions like acute pain and stiffness in the small joints with redness and swelling with fever. It cures fever associated with Pitta-kapha dominance.

In rheumatoid arthritis it is used to heal the inflammation and improve the function of the affected joints. It is beneficial even in cases of varicose veins with burning sensation and redness.

Ii is used to treat anaemia and hepatitis. It works as a hepato-protective formulation.

It is beneficial in gastric ulcer with severe burning sensation, heartburn and sour belching. In chronic peptic ulcer, Gudoochyadi ksheerakashaya is found effective.

It is used in the treatment of many skin diseases like atopic dermatitis, childhood eczema, heat rash, acne, oozing pustules, blisters, nail bed infections etc where redness, swelling and burning sensation are present.

It is used to treat hot flushes associated with menopause. It is beneficial in inflammatory vaginal diseases with redness and burning sensation.

Indications of Guluchyadi kashayam

Pitta-Kaphajwara            – Fever with Pitta and Kapha dominance

Chardi                                – Vomiting

Daha                                  – Burning sensation

Thrishna                           – Excess thirst and dryness of mouth

Agnikrit                             – Improves digestive fire

 Ingredients of Guluchyadi kashayam

Heart leaved moonseed Guluchi


Tinospora cordifolia (WILLD.) HOOK.F. & THOMS

It is effective anti-ulcer drug in action. It is a well-known anti-oxidant and has significant anti-inflammatory property.

Wild Himalayan cherry Padmaka Prunus cerasoides

It has anti-oxidants and is used to treat skin diseases and herpes. It is also used in vomiting, nausea and gastritis.

Margosa, Neem Arishta Azadirachta indica A. JUSS.


The important health benefits of this drug include its ability to treat dandruff, soothe irritation, protect the skin, boost the immune system, and reduce inflammation. It also speeds up wound healing, treats gastric conditions, slows the aging process, improves hair and scalp health, maintains sexual organ health, has anti-cancer potential, and helps treat diabetes.

Cilantro seeds Dhanyaka Corriandrum sativum Linn.

It is an anti-oxidant, anti-diabetic, diuretic, and anti-pyretic. It improves digestion and absorption; it is good for heart.

Red sandalwood Raktachandana Pterocarpus santalinus L.

It has anti-inflammatory, anti-pyretic, anthelmintic, aphrodisiac, anti-hyperglycaemic and diaphoretic properties. It is used in the treatment of fever, haemorrhage and dysentery.

 Details of the manufacturing

 Guluchyadi kashayam has five ingredients. Five of them are taken in equal quantity.

All these ingredients should be washed well and dried up in shade.

Take the prescribed herbs in dried & crushed form in an earthen pot. Now add 16 times clean water into it. Make it boil and then cook in the open vessel with low fire. Reduce the quantity into one by eighth of the initial quantity. Make sure to mix it in between with a wooden spatula. Also, the fire should be kept low to make sure that all the active ingredients in the herbs needed are absorbed well into the water. Once the quantity is reduced to one by eighth of the initial amount of water, remove the vessel from the fire. Squeeze and drain through a clean white cloth. Collect the decoction in a clean vessel and discard the solid waste. Drink the mild warm decoction.

Dosha Dooshya Predominance with roga margas.

Guluchyadi kashayam is Pitta-kaphahara.

It acts antar, madhyama and bahir-rogamargas.

 Dosage and Usage of Guluchyadi kashayam

Dosage: two Pala.


Kashayam is advised to take in empty stomach, once the ingested food is digested well and aahaararasa is formed well.

Usage of kashayam with prescribed prakshepadravyas according to the condition of disease and the patient gives the best results mostly.

As guduchyadi combination is mentioned as a Gana, it can be used as any Kalpana (preparation) kashaya, choorna, ghrita or taila. Most famous and widely used formulation is guduchyadi kashayam.

In some Niraama pitta conditions, Guduchyadi paalkashayam (decoction with milk) and guduchyadi ghrita are also found beneficial.

Exercises and Yoga.

Guluchyadi kashayam is used in a wide variety of diseases. Execises should be decided considering the disease also. While it targets mainly joints, vigorous exercises are not allowed in painful conditions.

Only stretching, moderate walking, and mild cardio exercises are advised. Also, specific yogacharya including bhujangaasana, salabhasana, vajrasana is recommended. Range of movement and flexibility must be considered while doing every exercise.

Sookshma sandhi vyayama (warming up small joints) is advised.

Regular exercise helps improve bioavailability of the medicine and food ingested and leads to positive health.

Yoga can maintain harmony within the body and with the surrounding system.




All the exercises and physical exertions must be decided and done under the supervision of a medical expert only.

Recommended diet and behaviour


  • To be avoided

Heavy meals and difficult to digest foods – cause indigestion.

junk foods- cause disturbance in digestion and reduces the bioavailability of the medicine

carbonated drinks – makes the stomach more acidic and disturbed digestion

refrigerated and frozen foods – causes weak and sluggish digestion by weakening Agni (digestive fire)

curd – causes vidaaha and thereby many other diseases

Red chilly and other pungent, hot and spicy food items.

  • To be added

Light meals and easily digestible foods

Green gram, soups, milk and ghee.

freshly cooked and warm food processed with cumin seeds, ginger, ajwain etc


Better to avoid exposure to excessive sunlight wind rain or dust.

Avoid sedentary lifestyle as it is one of the main causes of rheumatoid arthritis.

Maintain a regular food and sleep schedule.

Avoid holding or forcing the urges like urine, faeces, cough, sneeze etc.

Side effects and contraindications

No known side effects reported

Classical references


 Equivalent medicines.

Amrthotharam kashayam

Patolakaturohinyadi kashaym

 Brands Available

AVS Kottakal

AVN madurai


AVP Coimbatore

Nagarjuna Ayurveda

Kerala Ayurveda

Research papers



The objective of the present work is to study the antioxidant and anti-inflammatory effect of alcoholic and water extracts of T. cordifolia (Willd.) Miers leaves in activated human monocytic THP-1 cells.

  1. cordifolia (Willd.) Miers extracts exhibited significant amounts of total phenolic and flavonoid content, and LC-MS/MS analyses detected tinosponone, a TC-specific clerodane-derived diterpene. Both types of extracts attenuated AA-induced ROS generation via enhancing catalase enzyme activity in THP-1 cells. Real time PCR and ELISA experiments revealed that the elevated levels of LPS-induced TNF-α was remarkably attenuated in THP-1 cells pretreated with T. cordifolia (Willd.) Miers extracts. Western blot and confocal microscopy showed that the alcoholic extract’s anti-inflammatory activity by attenuating NF-κB translocation into the nucleus in LPS-activated THP-1 cells via the inhibition of IκB degradation in the cytosol.

The findings suggest that T. cordifolia (Willd.) Miers dry leaf extracts possess antioxidant and anti-inflammatory properties via upregulation of antioxidant enzymes and attenuation of NF- κB nuclear translocation in activated human monocytic (THP-1) cells.

doi: 10.1016/j.phymed.2019.152831.


Anti-oxidant property


Therapeutic roles


Effect on lipid metabolism


Therapeutic roles



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