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Vyaghryadi kashayam- Benefits, Ingredients, Indications, Dosage, Diet, Side effects, Research Papers


What is the Use of Vyaghryadi kashayam?


Vyaghryadi kashayam is an Ayurvedic medicine for improving respiratory health and immunity. It also helps to treat fever associated with respiratory tract infection.

Vyaghryadi kashayam  Benefits


It is very effective in the flare ups of asthma. It works as a good expectorant, removes the malaroopakapha and clears airways.

It is used in chronic dry cough at night, especially in children.

It is found useful in treating Kapha-Vata dominant fevers like dengue when added with other formulations.

As the kaphadosha is cleared, Agni starts functioning proper.

By improving digestion, this kashayam improves taste and appetite; bio availability of nutrients in the food also enhanced. Hence general health improved.

It is also effective in sinusits and headache.


Vaata Kapha jwara – highly virulent fevers like malaria, dengue etc

Swaasa               – breathing disorders including asthma

Kaasa                  -Cough

Peenasa              – Running nose and sinusitis

Soola                  – Headache, mostly KaphaVaataja

Vyaghryadi kashayam Ingredients


ENGLISH NAME: Wild Eggplant, Yellow – Berried Nightshade

LATIN NAME: Solanum surattense BURM. F.


Solanum jacquini WILLD.

Solanum sarmentosum NEES

Solanum xanthocarpum SCHRAD & WENDL


Solanum indicum L

Solanum anguivi LAM.

Gloriosa superba L.





General medicinal uses:

This plant has anthelmintic property. It is useful in bronchitis, asthma, fever, thirst and given in urinary concretions. This drug has good application for piles. The fruit is laxative. Fumigations with the vapour of the burning seeds of this plant are found useful for the cure of toothache.


ENGLISH NAME: Dried ginger

LATIN NAME: Zingiber officinalis





General medicinal uses:

It is unctuous and hot in potency with pungent taste but becomes sweet after digestion. It is an aphrodisiac and balances Vata and Kapha.

It improves ability to taste and promotes digestion. Relieves cough cold and other respiratory problems. It is not a laxative, rather causes constipation.


ENGLISH NAME: tinospora, heart leaved moonseed

LATIN NAME: Tinospora cordifolia (WILLD.) HOOK.F. & THOMS.


Cocculus cordifolius (WILLD.) DC.

Menispermum cordifolium WILLD.


Tinospora sinensis (LOUR.) MERR.





GENERAL MEDICINAL USES: it is anti-pyretic and anti-inflammatory. It is effective anti-ulcer in action. It works as a diuretic.



ENGLISH NAME: long pepper

LATIN NAME: Piper longum L.


Chavica roxburghii MIQ.





General medicinal uses:

It has carminative action and maybe used as appetizer. The fruit and root of Pippali are used in the form of powder to treat fever, diarrhoea, piles, cough, hiccough, asthma, hoarseness of voice, flatulence, colic, vomiting, acid gastritis, oedema, diseases of mouth, eye diseases, diseases of semen, diseases of women, jaundice, and earache

Cough: Pippali mixed with honey alleviates cough, dyspnoea, fever splenomegaly and hiccough. It is particularly recommended for children.

Details of the manufacturing

 As already discussed, Vyaghryadi kashayam is prepared using Vyaghri Guduchi and Sunthi as its ingredients with 6:4:2 ratio respectively.

All these ingredients should be washed well and dried up in shade.

Take the prescribed herbs in dried & crushed form in an earthen pot. For your special attention, Sunthi should be crushed and tied up separately in a white clean cotton cloth as a Potali. This is to prevent the excess dissolution of the contents and to maintain the exact consistency of the kashayam. Now add 16 times clean water into it. Make it boil and then cook in the open vessel with low fire. Reduce the quantity into one by eighth of the initial quantity. Make sure to mix it in between with a ladle without breaking the potli. Also, the fire should be kept low to make sure that all the active ingredients in the herbs needed are absorbed well into the water. Once the quantity is reduced to one by eighth of the initial amount of water, remove the vessel from the fire. Squeeze and drain through a clean white cloth. Collect the decoction in a clean vessel and discard the solid waste. Drink the mild warm decoction.

Dosha Dooshya Predominance with roga margas.

Vyaghryadi kashayam is kaphahara.

It acts on aabhyantara rogamarga

  Vyaghryadi kashayam Dosage

Dosage: two Pala.


Kashayam is advised to take in empty stomach, once the ingested food is digested well and aahaararasa is formed well.

Usage of kashayam with prescribed prakshepadravyas according to the condition of disease and the patient gives the best results mostly.

It is indicated in the shloka that Vyaghryadi kashayam should be taken with Pippalichoorna mixed in it.

Exercises and Yoga.

As Vyaghryadi kashayam targets mainly respiratory system and immunity, only mild exercises are advised. Also, specific yogacharya including naadeesuddhi pranayama, bhujangaasana, is recommended.

In persons with fever and respiratory infections, physical exercises are not recommended.

Regular exercise after regaining normal health helps improve bioavailability of the food ingested and leads to positive health.

Yoga can maintain harmony within the body and with the surrounding system.

Nadisudhi pranayama


Simple exercises for lungs and heart health

All the exercises and physical exertions must be decided and done under the supervision of a medical expert only.

Recommended diet and behaviour


  • To be avoided

Drinking ice-cold water – loss of appetite and increased kapha leads to respiratory problems.

Heavy meals and difficult to digest foods – cause indigestion.

junk foods- cause disturbance in digestion and reduces the bioavailability of the medicine

carbonated drinks – makes the stomach more acidic and disturbed digestion

refrigerated and frozen foods – causes weak and sluggish digestion by weakening Agni (digestive fire)

Milk and milk products – increase kapha and cause respiratory problems

curd – causes vidaaha and thereby many other diseases

  • To be added

Light meals and easily digestible foods

Green gram, soups, honey.

freshly cooked and warm food processed with cumin seeds, ginger, black pepper, ajwain etc


Protect yourself from cold climate.

Better to avoid exposure to excessive sunlight, wind, rain or dust.

Maintain a regular food and sleep schedule.

Avoid holding or forcing the urges like urine, faeces, cough, sneeze etc.

Side effects 

No known side effects reported.

 Classical references


 Equivalent medicines.

Dasamoolakaduthrayam kashayam

Brands Available

AVS Kottakal

AVP Coimbatore

AVN Madurai

Kerala ayurveda

Vyaghryadi Lehyam is also availabe

Research papers


 The study was undertaken to evaluate the antihyperglycemic and antihyperlipidemic effects of Piper longum root aqueous extract (PlrAqe) in streptozotocin (STZ) induced diabetic rats.

During the short term study the aqueous extract at a dosage of 200 mg/kg.b.w was found to possess significant antidiabetic activity after 6 h of the treatment. The administration of aqueous extract at the same dose for 30 days in STZ induced diabetic rats resulted in a significant decrease in FBG levels with the corrections of diabetic dyslipidemia compared to untreated diabetic rats. There was a significant decrease in the activities of liver and renal functional markers in diabetic treated rats compared to untreated diabetic rats indicating the protective role of the aqueous extract against liver and kidney damage and its non-toxic property.

it was concluded that the plant extract is capable of managing hyperglycemia and complications of diabetes in STZ induced diabetic rats.

doi: 10.1186/1472-6882-13-37

To compare stress resistance increasing and analgesic activities of piperlongumine and a methanolic Piper longum fruit extract (PLE).

significant effects of piperlongumine and PLE in both the tests were observed after their 5 or more daily doses. Both of them also dose dependently suppressed daily handling and repetitive testing triggered alterations in body weights and core temperatures. Their doxycycline like antidepressant activity in tail suspension test and aspirin like analgesic effects in acetic acid writhing test were observed after their 11 daily 5 mg/kg oral dose.

Piperlongumine is another bioactive secondary metabolite of P. longum and other plants of piper species with stress response suppressing, analgesic, and anti-inflammatory activities.

doi: 10.1016/j.jtcme.2015.11.001

To compare doxycycline (DOX) such as oral efficacies of piperlongumine (PL) and a Piper longum fruits extract (PLE) as stress resistance inducers.

Efficacies of oral pretreatments with 5 mg/kg PL or PLE or of 50 mg/kg DOX for 10 consecutive days against stress resistance were compared. Mice in treated groups were subjected to a stress induced hyperthermia on the 1st, 5th, 7th, and 10thday. Treated mice were then subjected to tail suspension test on the 11thday. Alteration in body weights, core temperatures, and gastric ulcers triggered by occasional exposures to foot shocks were determined.

PL and crude PLE are DOX like long-acting desensitizers of stress triggered co-morbidities. Reported observations add further experimental evidences justifying traditionally known medicinal uses of P. longum and other plants of the Piperaceae family, and reveal that PL is also another very long acting and orally active inducer of stress resistance. Efforts to confirm stress preventive potentials of low dose plant-derived products enriched in PL or piperine like amide alkaloids in volunteers and patients can be warranted.

doi: 10.5455/jice.20150921010411


The objective of the present work is to study the antioxidant and anti-inflammatory effect of alcoholic and water extracts of T. cordifolia (Willd.) Miers leaves in activated human monocytic THP-1 cells.

  1. cordifolia (Willd.) Miers extracts exhibited significant amounts of total phenolic and flavonoid content, and LC-MS/MS analyses detected tinosponone, a TC-specific clerodane-derived diterpene. Both types of extracts attenuated AA-induced ROS generation via enhancing catalase enzyme activity in THP-1 cells. Real time PCR and ELISA experiments revealed that the elevated levels of LPS-induced TNF-α was remarkably attenuated in THP-1 cells pretreated with T. cordifolia (Willd.) Miers extracts. Western blot and confocal microscopy showed that the alcoholic extract’s anti-inflammatory activity by attenuating NF-κB translocation into the nucleus in LPS-activated THP-1 cells via the inhibition of IκB degradation in the cytosol.

The findings suggest that T. cordifolia (Willd.) Miers dry leaf extracts possess antioxidant and anti-inflammatory properties via upregulation of antioxidant enzymes and attenuation of NF- κB nuclear translocation in activated human monocytic (THP-1) cells.

doi: 10.1016/j.phymed.2019.152831.


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